Automated Synthetic Biology Integrated System_Galatek

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Automated Synthetic Biology Integrated System
Automated Synthetic Biology Integrated System
Synthetic biology, often called the defining technology of modern biotechnology, represents the field's third major revolution—following the decoding of DNA and the Human Genome Project—by enabling direct genome design and construction. Integrating biology, engineering, and computational science, it shifts Life Sciences from observation-based study into a predictable, quantifiable, and engineerable discipline. With transformative potential across sectors—including medicine, agriculture, energy, and environmental sustainability—synthetic biology is rapidly translating scientific insight into real-world technologies, offering innovative pathways to address pressing global challenges.

Product Introduction

Hgh-Throughput Clone Picking Platform (Basic Version)

Hgh-Throughput Clone Picking Platform (Enhanced Version)

High-Throughput Plasmid Construction Platform

High-Throughput Strain Screening Platform

Fully Automatic Molecular Cloning Platform

Hgh-Throughput Clone Picking Platform (Basic Version)
Hgh-Throughput Clone Picking Platform (Basic Version)

Hgh-Throughput Clone Picking Platform (Basic Version) unifies a robotic arm, an automated colony picker, and modular stackers into a single system. Designed for flexibility, it allows for adaptable rack configuration to support seamless, walk-away automation for monoclonal colony selection and other related procedures.

Hgh-Throughput Clone Picking Platform (Enhanced Version)
Hgh-Throughput Clone Picking Platform (Enhanced Version)

The Hgh-Throughput Clone Picking Platform (Enhanced Version) seamlessly executes a complete molecular biology pipeline-from PCR amplification and ligation to transformation, clone selection, and culture. This integrated approach establishes a fully automated DNA assembly workflow, ensuring high fidelity and robust performance.

High-Throughput Plasmid Construction Platform
High-Throughput Plasmid Construction Platform

The High-Throughput Plasmid Construction Platform employs a modular architecture, integrating an embedded 4-axis collaborative robot, liquid handling workstation, PCR purification unit, reagent dispenser, automatic sealer, colony picker, and consumable storage modules. This configuration enables fully automated execution of the complete workflow spanning PCR amplification, ligation, transformation, colony selection, and strain cultivation. The intelligent software platform implements rigorous timing controls to maintain consistent experimental conditions across all sample batches, effectively addressing the cost, efficiency, and reliability limitations inherent in manual operations. This integrated solution not only enhances plasmid production yield and accuracy but also establishes a robust, high-fidelity automated pipeline for DNA assembly applications.

High-Throughput Strain Screening Platform
High-Throughput Strain Screening Platform

The High-Throughput Strain Screening Platform unifies multiple automation components including liquid handling systems, incubation units, and microplate readers into a coordinated workflow. It automates the entire strain screening procedure from colony picking and induced expression to reaction detection, while supporting parallel operations such as live culture expansion, cell density monitoring, and strain archiving. Featuring adaptive task scheduling capabilities, the system allows seamless integration of additional experimental capacity and dynamically accommodates evolving research requirements. This versatile solution finds broad application in the development and optimization of industrial microbial strains across sectors including enzyme production, food and beverage processing, and bioenergy.

Fully Automatic Molecular Cloning Platform
Fully Automatic Molecular Cloning Platform

The Fully Automatic Molecular Cloning Platform streamlines the entire bacterial strain screening workflow, seamlessly integrating steps from colony selection and expression induction through to final analysis. It accommodates a variety of screening methodologies and facilitates key parallel operations, including online vector construction, strain expansion and cultivation, optical density monitoring, and culture archiving.

Solution Feature

High Throughput
High Throughput
R&D production of 500 + plasmids in 8 hours by performing six 96-well plates in parallel.
Precise Micro-Sampling
Precise Micro-Sampling
The MicroPCR system can be constructed in the liquid workstation, and the cost of reagents is reduced by 20% compared with manual operations
Application Development
Application Development
The high-throughput automated transformation methods for bacteria and yeast have been developed; Plasmid extraction, nucleic acid purification and quantification reagents and automatic tip consumables are provided to reduce the use cost
Clear Data Flow
Clear Data Flow
A single hole-level data traceability mechanism can be provided, which is graphically displayed through Galatek’s data center for clarity and avoids cumbersome retrieval and correspondence of a large number of tables

Product Parameter

Product NameHgh-Throughput Clone Picking Platform (Basic Version)
Size2500*1900*2400mm
Throughput600-3000 clones/h
Environmental ControlDust cover, FFU, positive pressure laminar flow hood, etc.
Application RequirementIntegrate the equipment, robotic arms, and consumable stacks within a sterile environment to
enable high-throughput automated clone picking that is compatible with a variety of consumables.

Application Scenarios

Isolation of Environmental Microorganisms
Isolation of Environmental Microorganisms
Construction of Engineering Bacteria
Construction of Engineering Bacteria
Mutant Library Screening
Mutant Library Screening
Antibody Production
Antibody Production
Metabolic Engineering
Metabolic Engineering
Virus Packaging
Virus Packaging
Directed Evolution of  Strains
Directed Evolution of Strains
Raw Material Production
Raw Material Production
Drug Intermediate Development
Drug Intermediate Development
New Biological Energy Development
New Biological Energy Development
Enzyme Engineering
Enzyme Engineering
Study on Environmental Germplasm Resources
Study on Environmental Germplasm Resources

Solution Feature

High Picking Efficiency
High Picking Efficiency
600-3,000 clones can be picked per hour, and the consumable stacker can be configured to meet the requirements of plate and deep-well plate placement. The consumables can be replaced automatically by the robotic arm.
Sterile Environment
Sterile Environment
The negative pressure/dust cover environment control & UV sterilization module ensures that the workbench is clean and contamination-free
Compatible with a Variety of Plating Methods
Compatible with a Variety of Plating Methods
It supports multiple coating methods such as zig-zag and rectangular plating to obtain single colonies
Traceability of Sample Information Between Multiple Screening Rounds
Traceability of Sample Information Between Multiple Screening Rounds
Software supports visualization of the relationship between each well position and the previous and subsequent batches

Product Parameter

Product NameHgh-Throughput Clone Picking Platform (Enhanced Version)
Size2350*1000*2400mm
Throughput600-3000 clones/h; Plate spreading: ~3 minutes per plate
Environmental ControlDust cover, FFU, positive pressure laminar flow hood, etc.
Application RequirementCentered around the automated coating and clone picking equipments, applying bacterial
suspension onto; culture plates and selecting individual colonies automatically.

Application Scenarios

Isolation of Environmental Microorganisms
Isolation of Environmental Microorganisms
Construction of Engineering Bacteria
Construction of Engineering Bacteria
Mutant Library Screening
Mutant Library Screening
Antibody Production
Antibody Production
Metabolic Engineering
Metabolic Engineering
Virus Packaging
Virus Packaging
Directed Evolution of  Strains
Directed Evolution of Strains
Raw Material Production
Raw Material Production
Drug Intermediate Development
Drug Intermediate Development
New Biological Energy Development
New Biological Energy Development
Enzyme Engineering
Enzyme Engineering
Study on Environmental Germplasm Resources
Study on Environmental Germplasm Resources

Solution Feature

Liberate Manpower
Liberate Manpower
One device plus 1-2 experimenters can complete the manual operation of about 7 experimenters
High Throughput
High Throughput
R&D production of 500 + plasmids in 8 hours by performing six 96-well plates in parallel
Precise Micro-Sampling
Precise Micro-Sampling
The MicroPCR system can be constructed in the liquid workstation, and the cost of reagents is reduced by 20% compared with manual operations
Application Development
Application Development
The high-throughput automated transformation methods for bacteria and yeast have been developed; Plasmid extraction, nucleic acid purification and quantification reagents and automatic tip consumables are provided to reduce the use cost
Clear Data Flow
Clear Data Flow
A single hole-level data traceability mechanism can be provided, which is graphically displayed through Galatek’s data center for clarity and avoids cumbersome retrieval and correspondence of a large number of tables
Sterile Environment
Sterile Environment
The negative pressure/dust cover environment control & UV sterilization module ensures that the workbench is clean and contamination-free

Product Parameter

Product NameHigh-Throughput Plasmid Construction Platform
Size4800 *2500 *2400 mm
Throughput576 plasmid samples construction/day
Environmental ControlPositive pressure laminar flow, UV
Application Requirement

Conduct automatic progresses of gene assembly and plasmid extraction etc, to achieve target gene;amplification, ligation, transformation,

plate coating, monoclonal selection, and plasmid extraction.Meanwhile, operations including static plate culture, overnight bacterial culture,

and gel electrophoresis are performed offline separately.

Application Scenarios

Isolation of Environmental Microorganisms
Isolation of Environmental Microorganisms
Construction of Engineering Bacteria
Construction of Engineering Bacteria
Mutant Library Screening
Mutant Library Screening
Antibody Production
Antibody Production
Metabolic Engineering
Metabolic Engineering
Virus Packaging
Virus Packaging
Directed Evolution of  Strains
Directed Evolution of Strains
Raw Material Production
Raw Material Production
Drug Intermediate Development
Drug Intermediate Development
New Biological Energy Development
New Biological Energy Development
Enzyme Engineering
Enzyme Engineering
Study on Environmental Germplasm Resources
Study on Environmental Germplasm Resources

Solution Feature

Compatible with Multiple Screening Methods
Compatible with Multiple Screening Methods
It supports enzyme screening, metabolite screening, etc. in a variety of ways
AI Image Recognition of Strains
AI Image Recognition of Strains
It identifies bacteria, yeast and other strain wells by means of blue-white spots, fluorescence and other means to accurately pick target strains
Self-Developed  Plating Technology
Self-Developed Plating Technology
With the 1/8 well plating mode, the plating head can be sterilized and reused to prevent cross contamination
Flexibility
Flexibility
The usage of consumables is updated dynamically, consumables are used as needed, and the workstation table is released to reduce waste
Long Cycle Management
Long Cycle Management
Long-term stable monitoring of microbial cultivation process, real-time reminders of cultivation progress for multiple batches of synchronized processes, and triggering subsequent screening processes

Product Parameter

Product NameHigh-Throughput Strain Screening Platform
Size4600*2400*2300mm
Throughput960 bacterial samples/day
Environmental ControlPositive pressure laminar flow, UV
Application Requirement

Conduct the high-throughput strain screening process, to achieve amplification of bacterial cultures, OD600 

measurement, strain preservation, induction of expression, bacterial lysis, product purification, and detection.

Application Scenarios

Isolation of Environmental Microorganisms
Isolation of Environmental Microorganisms
Construction of Engineering Bacteria
Construction of Engineering Bacteria
Mutant Library Screening
Mutant Library Screening
Antibody Production
Antibody Production
Metabolic Engineering
Metabolic Engineering
Virus Packaging
Virus Packaging
Directed Evolution of  Strains
Directed Evolution of Strains
Raw Material Production
Raw Material Production
Drug Intermediate Development
Drug Intermediate Development
New Biological Energy Development
New Biological Energy Development
Enzyme Engineering
Enzyme Engineering
Study on Environmental Germplasm Resources
Study on Environmental Germplasm Resources

Solution Feature

One-Click Generation of Experiment Report
One-Click Generation of Experiment Report
The automated system is equipped with optional informatization functions, which utilize information technology to efficiently manage and analyze data. It converts data into formats suitable for AI model input and generates formatted tables within seconds, eliminating errors caused by manual data splicing while reducing over 90% of the workload.
Well-to-Well Sample Composite Information Traceability
Well-to-Well Sample Composite Information Traceability
Various information in the well position, such as antibiotics and strain information, will be tracked along with the pipetting action for visual data display, making it clear at a glance.
High-Throughput and High-Compatibility
High-Throughput and High-Compatibility
For each batch, it is possible to operate 384-756 plasmid construction procedures, and 480-960 strain screening procedures. It supports enzyme screening, metabolite screening, etc. in a variety of ways.
AI Image Recognition of Strains
AI Image Recognition of Strains
It identifies bacteria, yeast and other strain well by means of blue-white spots, fluorescence and other means to accurately pick target strains.

Product Parameter

Product NameFully Automatic Molecular Cloning Platform
Size5600*2500*2400 mm
ThroughputPlasmid construction process: 384-576 constructs per batch;
Strain screeningprocess: 480-960 strains per batch
Sample TypeEscherichia coli, yeast, etc.
Environmental ControlDust cover, FFU, positive pressure laminar flow hood, HEPA fltration, etc.
Application

Construction of engineering bacteria, Virus packaging, Directed evolution of strains, Raw material production, 

Drug intermediate development, Development of new biological energy, Enzyme engineering, Study on environmental 

germplasm resources, Study on directed evolution of microorganisms

Application Scenarios

Isolation of Environmental Microorganisms
Isolation of Environmental Microorganisms
Construction of Engineering Bacteria
Construction of Engineering Bacteria
Mutant Library Screening
Mutant Library Screening
Antibody Production
Antibody Production
Metabolic Engineering
Metabolic Engineering
Virus Packaging
Virus Packaging
Directed Evolution of  Strains
Directed Evolution of Strains
Raw Material Production
Raw Material Production
Drug Intermediate Development
Drug Intermediate Development
New Biological Energy Development
New Biological Energy Development
Enzyme Engineering
Enzyme Engineering
Study on Environmental Germplasm Resources
Study on Environmental Germplasm Resources

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